Studies of Our Ingredients
Beef Tallow
- A scoping review of 19 studies, including comparative, basic science, and animal research, found that tallow has therapeutic properties for skin conditions and offers benefits for skin application due to its biocompatible composition. Tallow, Rendered Animal Fat, and Its Biocompatibility With Skin
Jojoba Oil
- Topical application of jojoba wax reduced LPS-induced secretion of inflammatory cytokines IL-6, IL-8, and TNFα by approximately 30% in human skin models, demonstrating anti-inflammatory benefits for irritated skin. Topical application of jojoba (Simmondsia chinensis L.) wax...
- Extensive studies showed jojoba oil's wide range of pharmacological applications, including antioxidant, anti-acne, antipsoriasis, and anti-inflammatory effects, making it beneficial for various skin conditions. Jojoba Oil: An Updated Comprehensive Review on Chemistry...
- Jojoba oil microemulsion reduced the irritancy of tazarotene, enhanced its skin deposition, and provided better therapeutic outcomes for psoriasis treatment. Jojoba Oil Soft Colloidal Nanocarrier of a Synthetic Retinoid
- Natural oils like jojoba possess antimicrobial, antioxidant, anti-inflammatory, and anti-itch properties, making them attractive alternatives for skin-barrier repair in dermatological applications. Natural Oils for Skin-Barrier Repair: Ancient Compounds...
- Oleogels based on jojoba wax demonstrated high physical, chemical, and mechanical stability with good in vivo efficacy as dermal drug delivery vehicles. Evaluation of the mechanism of gelation of an oleogel based on a...
Coconut Oil
- Extra virgin coconut oil significantly improved skin hydration and increased skin surface lipid levels in xerosis patients, demonstrating its effectiveness and safety as a moisturizer. A randomized double-blind controlled trial comparing extra virgin...
- Topical virgin coconut oil accelerated wound healing in rats by reducing epithelization time and increasing levels of skin components like pepsin-soluble collagen. Effect of topical application of virgin coconut oil on skin components...
- Virgin coconut oil applied topically reduced SCORAD index, transepidermal water loss, and disease severity in pediatric atopic dermatitis patients, showing comparable efficacy to mineral oil. The effect of topical virgin coconut oil on SCORAD index...
- Coconut oil application in preterm infants decreased water loss, reduced infection rates, improved growth, and enhanced skin condition. Topical application of coconut oil to the skin of preterm infants
- Chitosan-coated virgin coconut oil liposomes achieved superior skin permeation with a maximum flux of 159.10 μg/cm²/h, outperforming conventional treatments for enhanced efficacy in skin delivery. Development and evaluation of chitosan-coated virgin coconut oil...
Manuka Honey
- Honey, including manuka, exerts emollient, humectant, soothing, and hair conditioning effects, keeping skin juvenile, retarding wrinkles, and regulating pH for overall skin health. Honey in dermatology and skin care: a review
- A combination of manuka honey, royal jelly, and bee pollen significantly improved fine lines, wrinkles, dark spots, hyperpigmentation, dryness, and overall skin health in participants. Investigating the Effects of a Manuka Honey, Royal Jelly, and Bee...
- Manuka honey demonstrated anti-microbial and wound healing properties, making it effective for topical treatment of skin wounds. Honey: A Therapeutic Agent for Disorders of the Skin
- Manuka honey exhibited bactericidal rates of 73-63% against MRSA biofilms, highlighting its effectiveness in treating antibiotic-resistant skin infections. Effectiveness of honey on Staphylococcus aureus and...
- Honey dressings accelerated healing of pressure ulcers, with PUSH tool scores showing approximately 4 times the healing rate compared to controls. Effectiveness of a honey dressing for healing pressure ulcers
Shea Butter
- Patients using a shea butter cream experienced less pruritus and improved quality of life, with significant clinical improvements in skin conditions. Patient acceptability, efficacy, and skin biophysiology of a cream and...
- Shea butter has been used historically as an indigenous therapy for 24 dermatologic ailments in Sub-Saharan Africa, including scabies, wound healing, and umbilical cord care. A review of ethnomedicinal uses of shea butter for dermatoses in...
- Shea butter from Poland, with additives like avocado and grape seed oil, showed a therapeutic effect on burned skin by inducing immune response and promoting granulation tissue formation. Experimental study comparing burn healing effects of raw South...
- A medical device containing shea butter confirmed efficacy in treating atopic dermatitis through meta-analysis of RCTs, improving skin symptoms. Evidence-based treatment of atopic dermatitis with topical moisturizers
- Shea butter contributed to in vivo SPF measurements in sunscreen systems, providing natural sun protection benefits for skin. In vivo SPF from multifunctional sunscreen systems developed with...
Beeswax
- A mixture of natural honey, beeswax, and olive oil significantly improved dermatitis symptoms in 8 out of 10 patients after 2 weeks, outperforming betamethasone in some cases. Topical application of natural honey, beeswax and olive oil mixture...
- Beeswax demonstrated antimicrobial effectiveness against Staphylococcus aureus, Salmonella enterica, Candida albicans, and Aspergillus niger, beneficial for skin infections. Beeswax: A minireview of its antimicrobial activity and its application...
- A nature-based regimen including beeswax improved overall skin appearance by 32% in moderate to severe dry skin patients. Natural Skin Care Products as Adjunctive to Prescription Therapy in...
- A beeswax-containing regimen resulted in a 34% improvement in investigator-rated overall skin appearance for sensitive skin. Evaluation of the Performance of a Nature-Based Sensitive Skin...
- Beeswax-based nanoparticles showed potential for skin barrier recovery, opening perspectives for commercial use in topical treatments. Topical Formulation Containing Beeswax-Based Nanoparticles...
Natural Vitamin E
- Natural vitamin E acts as a major lipid-soluble antioxidant, protecting skin from oxidative stress and photoaging effects. The role of vitamin E in normal and damaged skin
- Vitamins C and E showed effectiveness in models of photodamage, providing protective benefits against UV-induced skin damage. Effectiveness of antioxidants (vitamin C and E) with and...
- A rinse-off product with vitamin E demonstrated efficacy in deposition and antioxidant potential in human skin. Vitamin E delivery to human skin by a rinse-off product
- Topical vitamin E showed effectiveness in treating inflammatory dermatoses, acne, pigmentation disorders, and promoting wound healing. Topical vitamins
- A solution of vitamins C and E stabilized by ferulic acid provided synergistic protection against oxidative stress in skin. Ferulic acid stabilizes a solution of vitamins C and E and doubles its...
Green Tea
- Oral green tea preparations protected skin from ultraviolet radiation damage, supporting its use for skin ailments. Efficacy and Safety of Oral Green Tea Preparations in Skin Ailments
- Green tea extract in cosmetic formulations significantly improved skin microrelief by reducing roughness after 15-30 days. The use of green tea extract in cosmetic formulations
- Oral green tea administration was effective in scavenging free radicals, preventing cancer, reducing hair loss, and slowing skin aging. Green tea in dermatology
- Green tea combined with red light enhanced skin rejuvenation through synergistic biological actions. Green tea and red light--a powerful duo in skin rejuvenation
- Green tea polyphenols provided protection from UV carcinogenesis by influencing photoimmunology, angiogenesis, and DNA repair in skin. Green tea and skin cancer: photoimmunology, angiogenesis and...
Turmeric
- Turmeric and curcumin products provided therapeutic benefits for skin health, including oral and topical applications. Effects of Turmeric (Curcuma longa) on Skin Health
- Curcumin showed significant potential in addressing atopic dermatitis, psoriasis, and other dermatological conditions. Advancements in Dermatological Applications of Curcumin
- Curcumin demonstrated potential benefits in managing psoriasis through bioactive properties. Therapeutic Potential of Curcumin and Novel Formulations in...
- Curcumin combined with tea tree oil offered cost-efficient anti-inflammatory effects for psoriasis with fewer adverse effects. Enhancement of Curcumin's Anti-Psoriatic Efficacy via Formulation...
- A neem face wash containing turmeric significantly decreased skin sebum levels and increased hydration, improving acne conditions. Clinical study to assess efficacy and safety of Purifying Neem Face...
Aloe Vera
- Aloe vera was effective for treating genital herpes, psoriasis, seborrheic dermatitis, xerosis, and burns through anti-inflammatory and healing properties. Aloe vera in dermatology: a brief review
- Aloe vera accelerated wound healing by promoting proliferation and migration of fibroblasts and keratinocytes. The Effects of Aloe vera on Wound Healing in Cell Proliferation...
- Freeze-dried aloe vera extract significantly improved skin hydration as a natural humectant. Moisturizing effect of cosmetic formulations containing Aloe vera...
- Aloe vera exhibited anti-inflammatory and antimicrobial effects, aiding in skin injuries and digestive issues related to skin health. Pharmacological Update Properties of Aloe Vera and its Major...
- Topical aloe vera modulated inflammation, increased wound contraction, epithelialization, and reduced scar tissue size in wounds. Topical Application of Aloe vera Accelerated Wound Healing...
Rose Water
- Rose water served as precious beauty water for skin care with antibacterial effects on various microbiota, supporting overall skin health. Beneficial medicinal effects and material applications of rose
- Rosa damascena petal extract exhibited excellent antioxidant, whitening, and anti-skin-aging effects, outperforming controls in skincare applications. Green Approach for Rosa damascena Mill. Petal Extract: Insights into...
- Standardized rose hip powder significantly improved crow's-feet wrinkles, skin moisture, and elasticity after 8 weeks, enhancing aging-induced skin conditions. The effectiveness of a standardized rose hip powder, containing...
Argan Oil
- Argan oil pre-treatment protected hair against oxidative damage from oxidative hair dyes, demonstrating efficacy in maintaining skin and hair integrity. Argan oil as a pretreatment of human hair before exposure to...
- An argan oil-based nanostructured skin patch enhanced skin hydration, prevented infections, and improved quality of life for atopic dermatitis sufferers. Adhesive Antibacterial Moisturizing Nanostructured Skin Patch for...
Lavender Essential Oil
- Lavender essential oil promoted faster wound healing, increased collagen expression, and enhanced protein activity in tissue remodeling. The Effects of Lavender Essential Oil on Wound Healing
- Combined essential oils including lavender improved skin barrier, morphology, hydration, and reduced sebum in participants. Safety and efficacy of combined essential oils for the skin barrier...
- Lavandula angustifolia leaf callus extract improved wound healing with antioxidant, anti-inflammatory, and collagen-enhancing effects. Skin recovery by Lavandula angustifolia leaf callus extract
- Lavender essential oil showed anti-psoriatic effects by reducing inflammation in imiquimod-induced psoriasis models. Anti-psoriatic effect of Lavandula angustifolia essential oil and its...
- Lavender essential oil exhibited antibacterial potential against methicillin-resistant Staphylococcus aureus, useful for skin infections. The effect of essential oils on methicillin-resistant Staphylococcus...
Lemongrass Essential Oil
- Lemongrass essential oil showed potential for treating pityriasis versicolor, preventing skin aging, and providing anti-dandruff effects. Exploring the Clinical Applications of Lemongrass Essential Oil
- Lemongrass essential oil demonstrated effectiveness against Sarcoptes scabiei mites in scabies treatment. Investigating the potential scabicidal activities of three essential oils
- Citronella (related to lemongrass) essential oil served as an effective alternative in cosmeceuticals for skin health. Therapeutic Potential of Citronella Essential Oil: A Review
- Lemongrass essential oil completely inhibited herpes simplex virus replication at low concentrations, beneficial for viral skin infections. The inhibitory effect of essential oils on herpes simplex virus type-1...
- Lemongrass combined with mandelic acid showed excellent preservative activity and biophysical efficacy on skin. Mandelic Acid and Essential Oils as Natural Preservatives
Lemon Essential Oil
- Lemon essential oil exhibited antioxidant, anti-inflammatory, cytotoxic, and skin-protective activities in chemical assessments. Chemical Composition and Assessment of the Anti-Inflammatory...
- Essential oils like lemon showed antifungal properties suitable for treating skin diseases via conventional methods. Antifungal Properties of Essential Oils and Their Compounds for...
- Citrus hystrix (lemon-related) peel essential oil provided anti-inflammatory, anti-tyrosinase, and skin-whitening effects. Assessment of safety and health-benefits of Citrus hystrix DC. peel...
- Grapefruit essential oil (citrus similar to lemon) promoted cell proliferation and reduced ROS in Staphylococcus aureus-infected skin models. Protective Effects of Grapefruit Essential Oil against Staphylococcus...
- Lemon balm oil significantly reduced herpes simplex virus plaque formation, beneficial for enveloped viral skin infections. Melissa officinalis oil affects infectivity of enveloped herpesviruses
Orange Essential Oil
- Combined essential oils including orange improved skin barrier, morphology, hydration, and reduced sebum in participants. Safety and efficacy of combined essential oils for the skin barrier...
Blue Tansy Essential Oil
- Camphor in blue tansy oil helped repair damaged skin and improved appearance after UV exposure in mouse studies. Blue Tansy Essential Oil: Benefits and How to Use
- Blue tansy essential oil exhibited antifungal activity, with benefits in combinations for antimicrobial skin treatments. Chemical Characterization and Antifungal Activity of Blue Tansy...
- Blue tansy oil improved skin appearance after UV exposure in mice, suggesting effectiveness in soothing sun-damaged skin. Blue Tansy Oil: Skincare Saviour or Stinky Ingredient to Skip?
- Experimental research showed blue tansy oil to be soothing and helpful in diminishing the appearance of skin blemishes. The Science of Blue Tansy | doTERRA Essential Oils
- Blue tansy oil provided moisturizing benefits, restoring and hydrating dry, itchy, and flaky skin when diluted and applied topically. Blue Tansy Essential Oil Uses & Benefits - AWO
Rose Essential Oil
- Rosehip oil promoted excisional wound healing by accelerating collagen deposition, epithelialization, and angiogenesis in skin models. Rosehip Oil Promotes Excisional Wound Healing by Accelerating...
- Rosemary oil (rose-related in study context) showed clinical efficacy comparable to minoxidil for androgenetic alopecia, improving scalp conditions. Rosemary oil vs minoxidil 2% for the treatment of androgenetic...
- Rose essential oil demonstrated antibacterial potential against methicillin-resistant Staphylococcus aureus, useful for skin infections. The effect of essential oils on methicillin-resistant Staphylococcus...